FKBP1A anticorps (Middle Region)

N° du produit ABIN360055

Détail du produit anti-FKBP1A anticorps

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FKBP12.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FKBP12.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP1A / FKBP12 (FKBP1A Produits)

Synonymes: anticorps 12kDa, anticorps FKBP12, anticorps FKBP12-T1, anticorps FKBP12-T2, anticorps Fkbp, anticorps Fkbp1, anticorps mFKBP1, anticorps mFKBP12, anticorps FKBP-12, anticorps FKBP-1A, anticorps FKBP1, anticorps Rotamase, anticorps Fkbp12, anticorps ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12, anticorps ATFKBP12, anticorps FK506-binding protein 12, anticorps IMMUNOPHILIN, anticorps MSJ1.19, anticorps MSJ1_19, anticorps PKC12, anticorps PKCI2, anticorps PPIASE, anticorps FKBP1B, anticorps Fkbp2, anticorps fj02g10, anticorps zgc:73373, anticorps wu:fj02g10, anticorps FKBP1A, anticorps Bmfkbp13, anticorps zgc:103752, anticorps FK506 binding protein 1a, anticorps FK506 binding protein 1A, anticorps FK506-binding protein, anticorps FK506-binding protein 12, anticorps FK506 binding protein 1Aa, anticorps FK506 binding protein 1C, anticorps FK506-binding protein 59, anticorps FK506 binding protein like, anticorps FK506 binding protein 1A L homeolog, anticorps FK506 binding protein 1Ab, anticorps Fkbp1a, anticorps FKBP1A, anticorps Fkbp12, anticorps FKBP12, anticorps fkbp1aa, anticorps FKBP1C, anticorps EHI_180160, anticorps LOC5573443, anticorps Fkbp13, anticorps FKBPL, anticorps fkbp1a.L, anticorps fkbp1ab

Sujet: FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

ID gène: 2280, 9606

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process