PIK3R2 anticorps (Tyr467)

N° du produit ABIN360466

Détail du produit anti-PIK3R2 anticorps

Antigène: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Épitope: Tyr467

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PIK3R2.

Purification: Protein A column, followed by peptide affinity purification

Immunogène: This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PIK3R2

Antigène: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Autre désignation: PIK3R2 (PI3K p85b Produits)

Synonymes: anticorps MPPH, anticorps P85B, anticorps p85, anticorps p85-BETA, anticorps pik3r2, anticorps MGC80449, anticorps p85beta, anticorps phosphoinositide-3-kinase regulatory subunit 2, anticorps phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), anticorps phosphoinositide-3-kinase, regulatory subunit 2 (beta), anticorps PIK3R2, anticorps pik3r2, anticorps Pik3r2

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.Synonyms: PI 3 Kinase p85 beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphatidylinositol 3-kinase regulatory subunit beta

ID gène: 5296, 9606

UniProt: O00459

Pathways: VEGF Signaling, BCR Signaling