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PFKM anticorps (C-Term)

Cet anticorps anti-PFKM est un anticorps Lapin Polyclonal détectant PFKM dans WB, IHC (p) et EIA. Adapté pour Humain.
N° du produit ABIN360633

Aperçu rapide pour PFKM anticorps (C-Term) (ABIN360633)

Antigène

Voir toutes PFKM Anticorps
PFKM (phosphofructokinase, Muscle (PFKM))

Reactivité

  • 72
  • 31
  • 28
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 63
  • 11
  • 6
  • 4
Lapin

Clonalité

  • 64
  • 20
Polyclonal

Conjugué

  • 52
  • 8
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp PFKM est non-conjugé

Application

  • 65
  • 34
  • 30
  • 16
  • 15
  • 9
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Épitope

    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    This antibody reacts to PFKM.

    Purification

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PFKM.

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    PFKM (phosphofructokinase, Muscle (PFKM))

    Autre désignation

    PFKM

    Sujet

    Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.Synonyms: 6-phosphofructokinase muscle type, GSD7, PFK-1, PFK-A, PFK1, PFKX, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphofructokinase-M, Phosphohexokinase

    ID gène

    5213, 9606

    UniProt

    P08237

    Pathways

    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg
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