PFKM anticorps (C-Term)

N° du produit ABIN360633

Détail du produit anti-PFKM anticorps

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PFKM.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PFKM.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM (PFKM Produits)

Synonymes: anticorps GSD7, anticorps PFK-1, anticorps PFK1, anticorps PFKA, anticorps PFKX, anticorps AI131669, anticorps PFK-A, anticorps PFK-M, anticorps Pfk-4, anticorps Pfk4, anticorps Pfka, anticorps Pfkx, anticorps Pfk-M, anticorps M-PFK, anticorps PFKM, anticorps pfkm, anticorps zgc:92344, anticorps pfk, anticorps im:7137110, anticorps wu:fc58g11, anticorps phosphofructokinase, muscle, anticorps phosphofructokinase, platelet, anticorps phosphofructokinase, muscle a, anticorps phosphofructokinase, muscle S homeolog, anticorps phosphofructokinase, muscle b, anticorps PFKM, anticorps Pfkm, anticorps PFKP, anticorps pfkma, anticorps pfkm.S, anticorps pfkmb

Sujet: Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.Synonyms: 6-phosphofructokinase muscle type, GSD7, PFK-1, PFK-A, PFK1, PFKX, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphofructokinase-M, Phosphohexokinase

ID gène: 5213, 9606

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg