Hexokinase 1 anticorps (C-Term)

N° du produit ABIN360645

Détail du produit anti-Hexokinase 1 anticorps

Antigène: Hexokinase 1 (HK1)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to HK1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human HK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: Hexokinase-1 (HK1 Produits)

Synonymes: anticorps HK1-ta, anticorps HK1-tb, anticorps HK1-tc, anticorps HKD, anticorps HKI, anticorps HMSNR, anticorps HXK1, anticorps Hexokinase, anticorps hk1, anticorps HEX, anticorps HEX-1, anticorps HK, anticorps ARABIDOPSIS THALIANA HEXOKINASE 1, anticorps ATHXK1, anticorps F19B15.160, anticorps F19B15_160, anticorps GIN2, anticorps GLUCOSE INSENSITIVE 2, anticorps HEXOKINASE, anticorps hexokinase 1, anticorps im:7148527, anticorps wu:fc09d08, anticorps wu:fc16e02, anticorps wu:fc21e02, anticorps wu:fq14b11, anticorps zgc:55790, anticorps zgc:77618, anticorps hexokinase-1, anticorps HK1, anticorps BB404130, anticorps Hk-1, anticorps Hk1-s, anticorps dea, anticorps mHk1-s, anticorps HEXOKIN, anticorps Hxk1, anticorps NtHxK1, anticorps NtHxk, anticorps hexokinase, anticorps StHK1, anticorps hxk, anticorps hk1-A, anticorps hexokinase 1, anticorps hexokinase-1, anticorps Hexokinase 1, anticorps hexokinase 1, putative, anticorps hexokinase 1 L homeolog, anticorps HK1, anticorps hk1, anticorps LOC100136279, anticorps Hex1, anticorps HXK1, anticorps Hk1, anticorps TA19800, anticorps hxk1, anticorps LOC107797523, anticorps LOC102604144, anticorps hk1.L

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.Synonyms: Brain form hexokinase, HK1, Hexokinase type I

ID gène: 3098, 9606

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg