EDAR anticorps (Extracellular Domain)

N° du produit ABIN360882

Détail du produit anti-EDAR anticorps

Antigène: EDAR (Ectodysplasin A Receptor (EDAR))

Épitope: Extracellular Domain

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp EDAR est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects EDAR and cross reacts with human EDAR.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant extracellular domain of EDAR

Clone: 9A38

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EDAR

Antigène: EDAR (Ectodysplasin A Receptor (EDAR))

Autre désignation: EDAR (EDAR Produits)

Synonymes: anticorps rs3, anticorps edar, anticorps EDAR, anticorps MGC88893, anticorps DL, anticorps ECTD10A, anticorps ECTD10B, anticorps ED1R, anticorps ED3, anticorps ED5, anticorps EDA-A1R, anticorps EDA1R, anticorps EDA3, anticorps HRM1, anticorps dl, anticorps RGD1561714, anticorps ectodysplasin A receptor, anticorps ectodysplasin-A receptor, anticorps edar, anticorps EDAR, anticorps Edar

Sujet: EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR

ID gène: 13608

NCBI Accession: NP_034230

UniProt: Q9R187

Pathways: Tube Formation, Ubiquitin Proteasome Pathway