IL2 Receptor beta anticorps (Extracellular Domain)
Aperçu rapide pour IL2 Receptor beta anticorps (Extracellular Domain) (ABIN360905)
Antigène
Voir toutes IL2 Receptor beta (IL2RB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Specificité
- This antibody detects IL-2Rbeta.
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Purification
- Protein A/G affinity chromatography
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Immunogène
- Recombinant protein of IL-2Rbeta extracellular domain.
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Isotype
- IgG2
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Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Autre désignation
- CD122 / IL2RB
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Sujet
- IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
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ID gène
- 16185
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NCBI Accession
- NP_032394
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UniProt
- P16297
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Pathways
- Signalistation JAK/STAT, Growth Factor Binding
Antigène
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