IL20RA anticorps (Extracellular Domain)
Aperçu rapide pour IL20RA anticorps (Extracellular Domain) (ABIN360917)
Antigène
Voir toutes IL20RA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Specificité
- This antibody detects IL-20Ralpha.
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Purification
- Protein A/G affinity chromatography
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Immunogène
- Recombinant protein of IL-20Ralpha extracellular domain.
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Isotype
- IgG2
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Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL20RA (Interleukin 20 Receptor alpha (IL20RA))
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Autre désignation
- IL20RA
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Sujet
- The receptor for interleukin 20 is a heterodimer of 2 orphan class II cytokine receptor subunits, IL20RA, also called ZCYTOR7, and IL20RB, also called DIRS1. Binding assays demonstrated that IL20 bound to BHK transfectants expressing both IL20RA and IL20RB, but not to untransfected cells nor to transfectants expressing either receptor subunit alone. Binding of (125)I labeled IL20 was eliminated in the presence of 100 fold excess of unlabeled IL20 but not in the presence of 100 fold excess of the unrelated cytokine, IL21. The binding data revealed 88,000 IL20 receptors per cell, with a binding affinity of approximately 1.5 nM. Both receptor subunits were expressed in skin and were dramatically upregulated in psoriatic skin.Synonyms: Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, IL-20R-alpha, IL-20R1, Interleukin-20 receptor alpha chain, ZCYTOR7
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ID gène
- 237313
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NCBI Accession
- NP_766374
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UniProt
- Q6PHB0
Antigène
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