TREM1 anticorps (Extracellular Domain)

N° du produit ABIN360943

Cet anticorps Rat Monoclonal détecte spécifiquement TREM1 dans WB et IHC (fro). Il présente une réactivité envers Souris.

Aperçu rapide pour TREM1 anticorps (Extracellular Domain) (ABIN360943)

Antigène: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TREM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3C66

Détail du produit anti-TREM1 anticorps

Épitope: Extracellular Domain

Purification: Affinity Chromatography on Protein A/G.

Immunogène: Purified Mouse Recombinant TREM-1 extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western blotting: 1/500-1000. Immunohistochemistry on Frozen Sections: 1/50-100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 0.5 mg/mL.

Buffer: PBS without preservatives or stabilizers

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: The lyophilized IgG is stable at 2-8 °C for one month and for one year when kept at -20 °C. Reconstituted antibody can also be aliquotted and stored at -20 °C to -70 °C for 6 months without detectable loss of activity.

Date de péremption: 12 months

Détails sur TREM1

Antigène: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Autre désignation: TREM1

Sujet: TREM1 is also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. TREM1 is a Type I membrane protein that contains an immunoglobulin-like V-type domain. An alternatively spliced protein variant may be secreted. TREM1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes), TREM1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock.Synonyms: Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1

Poids moléculaire: 26 kDa

NCBI Accession: NM_021406

UniProt: Q9JKE2