SCARB2 anticorps (Internal Region)

N° du produit ABIN361195

Cet anticorps Chèvre Polyclonal détecte spécifiquement SCARB2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour SCARB2 anticorps (Internal Region) (ABIN361195)

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Classe de qualité: Verified

Détail du produit anti-SCARB2 anticorps

Épitope: Internal Region

Fonction: LIMP2 / SCARB2

Séquence: NKANIQFGDN GTTIS

Specificité: This antibody is expected to recognize reported isoform 1 (NP_005497.1) only.

Réactivité croisée: Humain, Souris

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-NKANIQFGDNGTTIS, from the internal region of the protein sequence according to NP_005497.1.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry: In paraffin embedded Human Cerebral Cortex shows lysosomal staining. Recommended concentration, 3-5 μg/mL.

Western Blot: Approx. 80 kDa band observed in Human Brain (Cortex and Cerebellum) lysates (calculated MW of 54.3 kDa according to NP_005497.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Fujita et

Peptide ELISA: antibody detection limit dilution 1:4000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Références pour anticorps anti-SCARB2 (ABIN361195)

Murphy, Gysbers, Abbott, Tayebi, Kim, Sidransky, Cooper, Garner, Halliday: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." dans: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SCARB2

Sujet: SCARB2, scavenger receptor class B, member 2, AMRF, CD36L2, HLGP85, LIMPII, 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane prote

ID gène: 950, 12492

NCBI Accession: NP_005497