DLG4 anticorps (N-Term)

N° du produit ABIN361381

Détail du produit anti-DLG4 anticorps

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Épitope: N-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG4 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for ~95k PSD-95 protein.

Réactivité croisée: Souris, Rat (Rattus)

Homologie: bovine, human, non-human primate, zebra fish

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur DLG4

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Autre désignation: DLG4 (DLG4 Produits)

Synonymes: anticorps 11, anticorps CG1725, anticorps CG1730, anticorps CPD, anticorps DLG, anticorps DLG-A, anticorps Discs-large, anticorps Dlg, anticorps Dlg-A, anticorps Dlg1, anticorps DlgA, anticorps Dmel\\CG1725, anticorps Drodlg, anticorps PSD95, anticorps SAP97, anticorps anon-EST:Posey93, anticorps anon-WO03040301.258, anticorps anon-WO03040301.260, anticorps anon-WO03040301.268, anticorps d. lg.-1, anticorps dlg, anticorps dlg-1, anticorps dlg-A, anticorps dlgA, anticorps dlgS97, anticorps l(1)10Bf, anticorps l(1)G0276, anticorps l(1)G0342, anticorps l(1)G0456, anticorps l(1)G19, anticorps l(1)L11, anticorps l(1)bwn, anticorps l(1)d.lg-1, anticorps l(1)d.lg.-1, anticorps l(1)discs large, anticorps l(1)dlg, anticorps l(1)dlg-1, anticorps l(1)dlg1, anticorps l(1)l.pr.-2, anticorps l(1)lpr-2, anticorps misb, anticorps dlgh4, anticorps psd95, anticorps sap90, anticorps sap-90, anticorps LLGL1, anticorps Dlgh4, anticorps PSD-95, anticorps SAP90, anticorps SAP90A, anticorps Sap90, anticorps SAP-90, anticorps DLG4, anticorps discs large 1, anticorps discs, large homolog 4, anticorps discs large MAGUK scaffold protein 4, anticorps discs, large homolog 4b (Drosophila), anticorps discs, large homolog 4 (Drosophila), anticorps dlg1, anticorps dlg4, anticorps DLG4, anticorps dlg4b, anticorps Dlg4

Sujet: PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004). Anti-PSD-95 Western blot of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~95k PSD-95 protein.

Poids moléculaire: '95 kDa

ID gène: 29495

UniProt: P31016

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity