RPH3A anticorps (C-Term)

N° du produit ABIN361408

Cet anticorps Lapin Polyclonal détecte spécifiquement RPH3A dans WB. Il présente une réactivité envers Rat.

Aperçu rapide pour RPH3A anticorps (C-Term) (ABIN361408)

Antigène: RPH3A (Rabphilin 3A (RPH3A))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPH3A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RPH3A anticorps

Épitope: C-Term

Specificité: Specific for the ~82k rabphilin 3A protein.

Réactivité croisée: Rat (Rattus)

Homologie: mouse, human, bovine, canine and non-human primate

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur RPH3A

Antigène: RPH3A (Rabphilin 3A (RPH3A))

Autre désignation: RPH3A

Sujet: Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington?s disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001). Anti- Rabphilin 3A Western blot of rat cortex lysate showing specific immunolabeling of the ~82k rabphilin 3A.

Poids moléculaire: '82 kDa

ID gène: 171039

UniProt: P47709

Pathways: Synaptic Vesicle Exocytosis