SYN1 anticorps
Aperçu rapide pour SYN1 anticorps (ABIN361409)
Antigène
Voir toutes SYN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Purification
- Antigen Affinity Purified from Pooled Serum
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Immunogène
- Native protein purified from bovine brain
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Indications d'application
- Recommended Dilution: WB: 1:1000 IHC, IF (frozen sections, unpublished observations): 1:2000 IP: 1 µg per 200 µg lysate Quality Control: Western blots performed on each lot.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized
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Stock
- -20 °C
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- SYN1 (Synapsin I (SYN1))
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Autre désignation
- SYN1
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Sujet
- Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989, Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Anti-Synapsin I Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein.
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Poids moléculaire
- '78 kDa
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ID gène
- 281510
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UniProt
- P17599
Antigène
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