Tyrosine Hydroxylase anticorps

N° du produit ABIN361414

Cet anticorps Mouton Polyclonal détecte spécifiquement Tyrosine Hydroxylase dans WB, IHC et IF. Il présente une réactivité envers Rat.

Aperçu rapide pour Tyrosine Hydroxylase anticorps (ABIN361414)

Antigène: Tyrosine Hydroxylase (TH)

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Tyrosine Hydroxylase anticorps

Specificité: Specific for the ~60k tyrosine hydroxylase protein.

Réactivité croisée: Mammifères

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 IF (frozen sections, unpublished observations): 1:1000 IHC (frozen sections, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur Tyrosine Hydroxylase

Antigène: Tyrosine Hydroxylase (TH)

Autre désignation: Tyrosine Hydroxylase

Sujet: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson?s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000, Salvatore et al., 2001). Anti-Tyrosine Hydroxylase Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k tyrosine hydroxylase protein.

Poids moléculaire: '60 kDa

ID gène: 25085

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour