GRIN2B anticorps (pTyr1336)

N° du produit ABIN361484

L’anticorps Lapin Polyclonal anti-GRIN2B a été validé pour WB, IHC et ELISA. Il convient pour détecter GRIN2B dans des échantillons de Rat. Il y a 3+ publications disponibles.

Aperçu rapide pour GRIN2B anticorps (pTyr1336) (ABIN361484)

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GRIN2B anticorps

Épitope: pTyr1336

Specificité: Specific for endogenous levels of the ~180 kDa NMDAR NR2B-subunit protein phosphorylated at Tyr1336 . Immunolabeling is completely eliminated by treatment with λ-phosphatase.

Réactivité croisée: Souris, Rat

Homologie: human, non-human primate

Attributs du produit: Our NMDA NR2B Subunit (Tyr1336) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects NMDA NR2B Subunit (Tyr1336) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1336 of the NR2B subunit of the rat NMDA receptor, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

Dilution Range: ICC: 1:100

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-GRIN2B (ABIN361484)

Jiang, Knox, Pathipati, Ferriero: "Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain." dans: Neuroscience letters, Vol. 503, Issue 3, pp. 215-9, (2011) (PubMed).

Hicklin, Wu, Radcliffe, Freund, Goebel-Goody, Correa, Proctor, Lombroso, Browning: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).

Chernova, Steinert, Guerin, Nicotera, Forsythe, Smith: "Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 32, pp. 8475-85, (2007) (PubMed).

Détails sur GRIN2B

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Autre désignation: GRIN2B

Sujet:

Synonyms: EPND antibody, FESD antibody, GluN2A antibody, Glutamate [NMDA] receptor subunit epsilon-1 antibody, Glutamate receptor antibody, Glutamate receptor ionotropic N methyl D aspartate 2A antibody, GRIN 2A antibody, GRIN2A antibody, hNR2A antibody, LKS antibody, N methyl D aspartate receptor channel subunit epsilon 1 antibody, N Methyl D Aspartate Receptor Subtype 2A antibody, N methyl D aspartate receptor subunit 2A antibody, N-methyl D-aspartate receptor subtype 2A antibody, NMDA receptor subtype 2A antibody, NMDAR 2A antibody, NMDAR2A antibody, NMDE1_HUMAN antibody, NR2A antibody, OTTHUMP00000160135 antibody, OTTHUMP00000174531 antibody

Description Logic: Our NMDA NR2B Subunit (Tyr1336) rabbit polyclonal phosphospecific primary antibody is produced . It detects NMDA NR2B Subunit (Tyr1336) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Gene Name Alternatives: GRIN2B

Poids moléculaire: 180 kDa

ID gène: 24410

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity