SYN1 anticorps (pSer9)

N° du produit ABIN361495

Détail du produit anti-SYN1 anticorps

Antigène: SYN1 (Synapsin I (SYN1))

Épitope: pSer9

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for ~78k synapsin I doublet protein phosphorylated at Ser9. The antibody also weakly labels the ~55k synapsin II protein which has a similar phosphorylation site to that of Ser9 on synapsin I. Immunolabeling is blocked by preadsorption of the antibody with the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Immunolabeling is also completely eliminated by treatment withphosphatase.

Réactivité croisée: Souris, Rat (Rattus)

Homologie: bovine, human, Xenopus, zebra fish

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 IHC: 1:500 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Références pour anticorps anti-SYN1 (ABIN361495)

Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: "ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).

Shimomura, Nagamine, Hatano, Sueyoshi, Kameshita: "Identification of an endogenous substrate of zebrafish doublecortin-like protein kinase using a highly active truncation mutant." dans: Journal of biochemistry, Vol. 147, Issue 5, pp. 711-22, (2010) (PubMed).

Détails sur SYN1

Antigène: SYN1 (Synapsin I (SYN1))

Autre désignation: SYN1 (SYN1 Produits)

Synonymes: anticorps SYN1a, anticorps SYN1b, anticorps SYNI, anticorps Syn-1, anticorps SYN I, anticorps si:dkey-90n12.3, anticorps synapsin I, anticorps synapsin I L homeolog, anticorps SYN1, anticorps Syn1, anticorps syn1.L, anticorps syn1

Poids moléculaire: '78 kDa

ID gène: 281510

UniProt: P17599