Tyrosine Hydroxylase anticorps (pSer31)
Aperçu rapide pour Tyrosine Hydroxylase anticorps (pSer31) (ABIN361502)
Antigène
Voir toutes Tyrosine Hydroxylase (TH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer31
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Specificité
- Specific for endogenous levels of the ~60 kDa tyrosine hydroxylase protein phosphorylated at Ser31.
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- non-human primate
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Attributs du produit
- Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.
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Purification
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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Immunogène
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31 of rat tyrosine hydroxylase, conjugated to keyhole limpet hemocyanin (KLH).
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Isotype
- IgG
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Indications d'application
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Dilution Range: ICC: 1:50-1:300
Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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Stock
- -20 °C
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Stockage commentaire
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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Date de péremption
- 12 months
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: "Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations." dans: Addiction biology, Vol. 19, Issue 2, pp. 145-55, (2014) (PubMed).
: "Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 2, pp. 466-78, (2014) (PubMed).
: "Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme." dans: Biochemical and biophysical research communications, Vol. 407, Issue 2, pp. 343-7, (2011) (PubMed).
: "Acute administration of cocaine regulates the phosphorylation of serine-19, -31 and -40 in tyrosine hydroxylase." dans: Journal of neurochemistry, Vol. 82, Issue 2, pp. 382-8, (2002) (PubMed).
: "Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ." dans: Journal of neurochemistry, Vol. 79, Issue 2, pp. 349-60, (2001) (PubMed).
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: "Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations." dans: Addiction biology, Vol. 19, Issue 2, pp. 145-55, (2014) (PubMed).
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- Tyrosine Hydroxylase (TH)
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Autre désignation
- Tyrosine Hydroxylase
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Sujet
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Synonyms: Dystonia 14 antibody, DYT14 antibody, DYT5b antibody, EC 1.14.16.2 antibody, OTTHUMP00000011225 antibody, OTTHUMP00000011226 antibody, ple antibody, Protein Pale antibody, TH antibody, The antibody, TY3H_HUMAN antibody, TYH antibody, Tyrosine 3 hydroxylase antibody, Tyrosine 3 monooxygenase antibody, Tyrosine 3-hydroxylase antibody, Tyrosine 3-monooxygenase antibody, Tyrosine hydroxylase antibody
Description Logic: Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced . It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.
Gene Name Alternatives: TH
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Poids moléculaire
- 60 kDa
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ID gène
- 25085
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UniProt
- P04177
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Pathways
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Antigène
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