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Tyrosine Hydroxylase anticorps (pSer31)

L’anticorps Lapin Polyclonal anti-Tyrosine Hydroxylase a été validé pour WB, IHC, ICC et ELISA. Il convient pour détecter Tyrosine Hydroxylase dans des échantillons de Rat. Il y a 5+ publications disponibles.
N° du produit ABIN361502

Aperçu rapide pour Tyrosine Hydroxylase anticorps (pSer31) (ABIN361502)

Antigène

Voir toutes Tyrosine Hydroxylase (TH) Anticorps
Tyrosine Hydroxylase (TH)

Reactivité

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Rat

Hôte

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Lapin

Clonalité

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Polyclonal

Conjugué

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Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA
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    pSer31

    Specificité

    Specific for endogenous levels of the ~60 kDa tyrosine hydroxylase protein phosphorylated at Ser31.

     Réactivité croisée

    Humain, Souris, Rat

    Homologie

    non-human primate

    Attributs du produit

    Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

    Purification

    Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

    Immunogène

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31 of rat tyrosine hydroxylase, conjugated to keyhole limpet hemocyanin (KLH).

    Isotype

    IgG
  • Indications d'application

    Dilution Range: ICC: 1:50-1:300

    Dilution Range: WB Brain: 1:1000

    Dilution Range: WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    Stock

    -20 °C

    Stockage commentaire

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    Date de péremption

    12 months
  • Calipari, Ferris, Melchior, Bermejo, Salahpour, Roberts, Jones: "Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations." dans: Addiction biology, Vol. 19, Issue 2, pp. 145-55, (2014) (PubMed).

    Izumi, Ezumi, Takada-Takatori, Akaike, Kume: "Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 2, pp. 466-78, (2014) (PubMed).

    Nakashima, Mori, Kaneko, Hayashi, Nagatsu, Ota: "Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme." dans: Biochemical and biophysical research communications, Vol. 407, Issue 2, pp. 343-7, (2011) (PubMed).

    Jedynak, Ali, Haycock, Hope: "Acute administration of cocaine regulates the phosphorylation of serine-19, -31 and -40 in tyrosine hydroxylase." dans: Journal of neurochemistry, Vol. 82, Issue 2, pp. 382-8, (2002) (PubMed).

    Salvatore, Waymire, Haycock: "Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ." dans: Journal of neurochemistry, Vol. 79, Issue 2, pp. 349-60, (2001) (PubMed).

  • Antigène

    Tyrosine Hydroxylase (TH)

    Autre désignation

    Tyrosine Hydroxylase

    Sujet

    Synonyms: Dystonia 14 antibody, DYT14 antibody, DYT5b antibody, EC 1.14.16.2 antibody, OTTHUMP00000011225 antibody, OTTHUMP00000011226 antibody, ple antibody, Protein Pale antibody, TH antibody, The antibody, TY3H_HUMAN antibody, TYH antibody, Tyrosine 3 hydroxylase antibody, Tyrosine 3 monooxygenase antibody, Tyrosine 3-hydroxylase antibody, Tyrosine 3-monooxygenase antibody, Tyrosine hydroxylase antibody

    Description Logic: Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced . It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

    Gene Name Alternatives: TH

    Poids moléculaire

    60 kDa

    ID gène

    25085

    UniProt

    P04177

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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