PLK1 anticorps (pSer482, pSer486, pSer490)
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- Antigène Voir toutes PLK1 Anticorps
- PLK1 (Polo-Like Kinase 1 (PLK1))
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Épitope
- pSer482, pSer486, pSer490
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Reactivité
- Xenopus laevis
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PLK1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Specific for the ~120k PLKK protein phosphorylated at Ser482,486,490.
- Réactivité croisée
- Xenopus laevis
- Homologie
- rat, mouse human, zebra fish
- Purification
- Antigen Affinity Purified from Pooled Serum
- Immunogène
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH
- Top Product
- Discover our top product PLK1 Anticorps primaire
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- Indications d'application
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Stock
- -20 °C
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- Antigène
- PLK1 (Polo-Like Kinase 1 (PLK1))
- Autre désignation
- PLK1 (PLK1 Produits)
- Synonymes
- anticorps PLK, anticorps STPK13, anticorps plk, anticorps PLK-1, anticorps Plx1, anticorps stpk13, anticorps Plk, anticorps cb525, anticorps cb636, anticorps ik:tdsubc_2d1, anticorps wu:fb37g11, anticorps wu:fb76g03, anticorps xx:tdsubc_2d1, anticorps polo like kinase 1, anticorps polo like kinase 1 S homeolog, anticorps polo-like kinase 1, anticorps polo-like kinase 1 (Drosophila), anticorps Serine/threonine-protein kinase plk-1, anticorps PLK1, anticorps plk1.S, anticorps plk1, anticorps Plk1, anticorps plk-1
- Sujet
- Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.
- Poids moléculaire
- '120 kDa
- ID gène
- 380481
- UniProt
- P70032
- Pathways
- Cycle Cellulaire, M Phase
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