GRIA2 anticorps (pSer880)

N° du produit ABIN362378

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIA2 dans WB. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour GRIA2 anticorps (pSer880) (ABIN362378)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIA2 anticorps

Épitope: pSer880

Specificité: The antibody detects endogenous level of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: Peptide sequence around phosphorylation site of pSer880 (I-E-S (p) -V-K) derived from Human Glutamate receptor 2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: Glutamate receptor 2 (Precursor)

Sujet: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Poids moléculaire: 100 kDa

NCBI Accession: NP_000817

UniProt: P42262

Pathways: Signalisation PI3K-Akt