CAMKII gamma anticorps (AA 284-288)

N° du produit ABIN362984

Cet anticorps Lapin Polyclonal détecte spécifiquement CAMKII gamma dans WB et IF. Il présente une réactivité envers Humain, Rat et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour CAMKII gamma anticorps (AA 284-288) (ABIN362984)

Antigène: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMKII gamma est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CAMKII gamma anticorps

Épitope: AA 284-288

Specificité: The antibody detects endogenous level of total CaMKII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogène: Peptide sequence around AA 284-288 (Q-E-T-V-D) derived from Human CaMKII. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Références pour anticorps anti-CAMKII gamma (ABIN362984)

Bossuyt, Helmstadter, Wu, Clements-Jewery, Haworth, Avkiran, Martin, Pogwizd, Bers: "Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure." dans: Circulation research, Vol. 102, Issue 6, pp. 695-702, (2008) (PubMed).

Détails sur CAMKII gamma

Antigène: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Autre désignation: CaMKII

Sujet: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity J Bossuyt, K Helmstadter, X Wu, et al. (2008) Ca2+/Calmodulin-Dependent Protein Kinase II {delta} and Protein Kinase D Overexpression Reinforce - Circulation Research, 102(6):695-702.

Poids moléculaire: 50 kDa

NCBI Accession: NP_150284

UniProt: P11798

Pathways: Signalisation WNT, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity