Cet anticorps anti-HDAC4/HDAC5/HDAC9 est un anticorps Lapin Polyclonal détectant HDAC4/HDAC5/HDAC9 dans WB, IHC et IF. Adapté pour Humain et Souris.
N° du produit ABIN363088
Aperçu rapide pour HDAC4/HDAC5/HDAC9 anticorps (AA 244-248) (ABIN363088)
Antigène
HDAC4/HDAC5/HDAC9
(HDAC4,HDAC5,HDAC9)
Reactivité
Humain, Souris
Hôte
Lapin
Clonalité
Polyclonal
Conjugué
Cet anticorp HDAC4/HDAC5/HDAC9 est non-conjugé
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Épitope
AA 244-248
Specificité
The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.
Immunogène
Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Reactivité: Humain
Hôte: Lapin
Polyclonal
Alexa Fluor 555
Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
HDAC4/HDAC5/HDAC9
(HDAC4,HDAC5,HDAC9)
Autre désignation
HDAC4/HDAC5/HDAC9
Sujet
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.