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HDAC4/HDAC5/HDAC9 anticorps (AA 244-248)

Cet anticorps anti-HDAC4/HDAC5/HDAC9 est un anticorps Lapin Polyclonal détectant HDAC4/HDAC5/HDAC9 dans WB, IHC et IF. Adapté pour Humain et Souris.
N° du produit ABIN363088

Aperçu rapide pour HDAC4/HDAC5/HDAC9 anticorps (AA 244-248) (ABIN363088)

Antigène

HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

Reactivité

  • 21
  • 11
  • 1
Humain, Souris

Hôte

  • 21
Lapin

Clonalité

  • 21
Polyclonal

Conjugué

  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp HDAC4/HDAC5/HDAC9 est non-conjugé

Application

  • 7
  • 5
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Épitope

    • 11
    • 10
    • 9
    • 2
    • 1
    • 1
    AA 244-248

    Specificité

    The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.

    Immunogène

    Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    Isotype

    IgG
  • Indications d'application

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène

    HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

    Autre désignation

    HDAC4/HDAC5/HDAC9

    Sujet

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

    Poids moléculaire

    124 kDa

    NCBI Accession

    NP_055522, NP_001015

    UniProt

    Q9UKV0
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