PLTP anticorps

N° du produit ABIN363330

Cet anticorps anti-PLTP Polyclonal Lapin (ABIN363330) détecte spécifiquement PLTP dans WB, IHC, ICC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PLTP anticorps (ABIN363330)

Antigène: PLTP (Phospholipid Transfer Protein (PLTP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLTP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-PLTP anticorps

Specificité: Reacts with PLTN from human and mouse

Purification: Antiserum

Immunogène: A partial peptide of human PLTP

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 - IHC - P : 1/500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: , Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur PLTP

Antigène: PLTP (Phospholipid Transfer Protein (PLTP))

Sujet: PLTP (phospholipid transfer protein) belongs to lipid transfer/lipopolysaccharide-binding proteins (BPI/LBP) family and it is a monomeric sectered protein expressed ubiquitously with highest expression in liver, one of the major sites of lipoprotein production and degradation. PLTP converts HDL into larger and smaller particles, and play a key role in extracellular phospholipid transport as well as modulation of HDL particles. Plasma PLTP is also considered a nonspecific lipid transfer protein because, along with phospholipids, it can also transfer alpha-tocopherol, diacylglycerol, cerebroside, and lipopolysaccharides. PLTP deficient mice depicts lowered susceptibility for atherosclerosis, whereas, PLTP transgenic mice have more atherosclerosis. In humans, an increased PLTP activity been linked to several conditions including type I/II diabetes mellitus, metabolic syndrome, obesitas, increased risk of coronary artery disease and cardiovascular disease.

Pathways: Lipid Metabolism