EPAS1 anticorps (C-Term)

N° du produit ABIN363383

L’anticorps Lapin Polyclonal anti-EPAS1 a été validé pour WB, IHC, ELISA, IP, ICC, FACS, IF, ChIP et GS. Il convient pour détecter EPAS1 dans des échantillons de Humain, Rat, Souris et Poisson.

Aperçu rapide pour EPAS1 anticorps (C-Term) (ABIN363383)

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reactivité: Humain, Rat, Souris, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPAS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)

Détail du produit anti-EPAS1 anticorps

Épitope: C-Term

Specificité: Reacts with mouse, rat, fish and human HIF-2 alpha

Réactivité croisée (Details): Does not cross-react with HIF-1 alpha.

Purification: Antigen affinity purified

Immunogène: Synthetic peptide derived from the C-term domain of mouse/human HIF-2 alpha protein.

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1.0 μg/mL - 2.0 μg/mL ChIP1:10-1:500 ELISA 1:100-1:2000 ICC/IF1:100 IHC 1:100 IP5 μg/1 mg lysate

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Détails sur EPAS1

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Autre désignation: Hypoxia-Inducible Factor 2-alpha

Sujet: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung.

ID gène: 2034

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg