LC3B anticorps (N-Term)

N° du produit ABIN363542

L’anticorps Lapin Polyclonal anti-LC3B a été validé pour WB, IHC, IF, FACS, ICC et IEM. Il convient pour détecter LC3B dans des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour LC3B anticorps (N-Term) (ABIN363542)

Antigène: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LC3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Détail du produit anti-LC3B anticorps

Épitope: N-Term

Specificité: Reacts with LC3B from human, mouse, rat and bovine and Zebrafish

Réactivité croisée (Details): Other species have not been tested.

Purification: Antigen affinity purified

Immunogène: Synthetic peptide made to the N-terminal region of the human LC3, isoform B protein

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF(1:2000) FC (1:200) IHC (1:400) WB (1:1000)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur LC3B

Antigène: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Autre désignation: Light Chain 3 beta (LC3B)

Sujet: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

ID gène: 81631

Pathways: Autophagy