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APP anticorps (AA 18-289)

L’anticorps Souris Monoclonal anti-APP a été validé pour WB, ELISA, IHC et IHC (p). Il convient pour détecter APP dans des échantillons de Humain et Souris.
N° du produit ABIN364364

Aperçu rapide pour APP anticorps (AA 18-289) (ABIN364364)

Antigène

Voir toutes APP Anticorps
APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivité

  • 239
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Humain, Souris

Hôte

  • 205
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  • 4
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Souris

Clonalité

  • 223
  • 65
  • 1
Monoclonal

Conjugué

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Cet anticorp APP est non-conjugé

Application

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

J4H9
  • Épitope

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    • 1
    AA 18-289

    Marque

    IHC-plus™

    Purification

    Protein G purified

    Immunogène

    Recombinant human APP (18-289aa) purified from E. coli.

    Type of Immunogen: Recombinant protein

    Isotype

    IgG2b kappa
  • Indications d'application

    Approved: ELISA, IHC, IHC-P (2.5 μg/mL), WB (1:500 - 1:1000)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.1 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    APP (Amyloid beta (A4) Precursor Protein (APP))

    Autre désignation

    APP / beta Amyloid

    Sujet

    Name/Gene ID: APP
    Family: Amyloid precursor protein

    Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II

    ID gène

    351

    UniProt

    P05067

    Pathways

    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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