CD72 anticorps
Aperçu rapide pour CD72 anticorps (ABIN371001)
Antigène
Voir toutes CD72 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa). It blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)
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Attributs du produit
- Synonyms: Lyb-2, Ly-32, Ly32, B-Cell marker, B-cell differentiation antigen CD72, Lymphocyte antigen32
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Purification
- Purified
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Immunogène
- DBA/2 mouse spleen cells. (Ref. 1)
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Isotype
- IgG2b
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Indications d'application
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Flow Cytometry. (Ref.1,2)Functional Assays: In vitro blocking and proliferation assays. (Ref.2,3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- CD72 (CD72 Molecule (CD72))
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Autre désignation
- CD72
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Sujet
- Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
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ID gène
- 100504743
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UniProt
- P21855
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Pathways
- BCR Signaling
Antigène
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