TUBB3 anticorps

N° du produit ABIN371847

Cet anticorps anti-TUBB3 Monoclonal Souris (Clone AA10) (ABIN371847) détecte spécifiquement TUBB3 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour TUBB3 anticorps (ABIN371847)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AA10

Détail du produit anti-TUBB3 anticorps

Specificité: AM08272PU-N is specific for the ~55 kDa beta III Tubulin protein. Note: This clone is similar to the Monoclonal antibody Tuj1.

Réactivité croisée (Details): Species reactivity (tested):Rat.

Attributs du produit: Synonyms: Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4

Purification: Protein G Chromatography.

Immunogène: Synthetic peptide corresponding to beta III tubulin.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/10,000. Immunohistochemistry: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: TUBB3 / TUBB4

Sujet: Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

ID gène: 246118

UniProt: Q4QRB4

Pathways: Dynamique des Microtubules, M Phase