Acetylcholinesterase anticorps (N-Term)

N° du produit ABIN372290

L’anticorps Lapin Polyclonal anti-Acetylcholinesterase a été validé pour WB et IHC (p). Il convient pour détecter Acetylcholinesterase dans des échantillons de Humain.

Aperçu rapide pour Acetylcholinesterase anticorps (N-Term) (ABIN372290)

Antigène: Acetylcholinesterase (AChE)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetylcholinesterase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Acetylcholinesterase anticorps

Épitope: N-Term

Specificité: This antibody recognizes Acetylcholinesterase (ACHE).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to N-terminal residues of Human Acetylcholinesterase (N- terminal extended acetylcholinesterase).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Acetylcholinesterase

Antigène: Acetylcholinesterase (AChE)

Autre désignation: Acetylcholinesterase

Sujet: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.Synonyms: AChE, Acetylcholine Esterase, Acetylcholine-Esterase

Poids moléculaire: 68 kDa.

ID gène: 43

NCBI Accession: NP_000656

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development