TLX1 anticorps (AA 300-330)

N° du produit ABIN372448

Détail du produit anti-TLX1 anticorps

Antigène: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Épitope: AA 300-330

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognizes Homeobox Protein Hox-11 (TLX1).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogène: Synthetic peptide corresponding to a portion of amino acids 300-330 of human HOX11.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur TLX1

Antigène: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Autre désignation: TLX1 (TLX1 Produits)

Synonymes: anticorps Hox-11, anticorps Hox11, anticorps HOX11, anticorps TCL3, anticorps XHox11, anticorps XHox11L2, anticorps hox11, anticorps tlx1-a, anticorps TLX-1, anticorps RGD1563655, anticorps SI:dZ46P4.1, anticorps Tlx-1, anticorps ztlx-1, anticorps T cell leukemia, homeobox 1, anticorps T-cell leukemia homeobox 1, anticorps T-cell leukemia homeobox 1 L homeolog, anticorps T-cell leukemia, homeobox 1, anticorps Tlx1, anticorps TLX1, anticorps tlx1.L, anticorps tlx1

Sujet: HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.Synonyms: HOX11, Hox-11, T-cell leukemia homeobox protein 1, T-cell leukemia/lymphoma protein 3, TCL-3, TCL3, TLX-1

ID gène: 3195

NCBI Accession: NP_005512

UniProt: P31314