TMEM123 anticorps (AA 173-188)

N° du produit ABIN372449

L’anticorps anti-TMEM123 Polyclonal Lapin est utilisé pour la détection de TMEM123 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Poulet. Il a été validé pour WB et IHC (p).

Aperçu rapide pour TMEM123 anticorps (AA 173-188) (ABIN372449)

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM123 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TMEM123 anticorps

Épitope: AA 173-188

Séquence: SRRGIRYRTI DEHDAI

Specificité: This antibody recognizes TMEM123/Porimin.

Réactivité croisée (Details): Species reactivity (expected):Bovine (Cow), Chicken, Mouse and Rat.
Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogène: Synthetic peptide corresponding to amino acids 173-188 of human Porimin.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur TMEM123

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Autre désignation: TMEM123 / Porimin

Sujet: Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.Synonyms: KCT-3, KCT3, Keratinocytes-associated transmembrane protein 3, PSEC0111, Pro-oncosis receptor inducing membrane injury, Transmembrane protein 123

ID gène: 114908

NCBI Accession: NP_443164

UniProt: Q8N131

Pathways: Regulation of Cell Size