Dynamin 1 anticorps (pSer778)
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- Antigène Voir toutes Dynamin 1 (DNM1) Anticorps
- Dynamin 1 (DNM1)
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Épitope
- pSer778
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet
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Hôte
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Mouton
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Dynamin 1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Specific for the ~95k dynamin protein phosphorylated at Ser778. This antibody labels the purified protein phosphorylated in vitro by CDK5 but not by PKC. Does not cross react with other purified substrates of CDK5 (e.g. Amphiphysin and Synapsin). Immunolabeling is blocked by lambda-phosphatase treatment.
- Réactivité croisée (Details)
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Species reactivity (expected):Human, Bovine, Canine, Chicken and Mouse.
Species reactivity (tested):Rat. - Purification
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Immunogène
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser778 of rat Dynamin.
- Isotype
- IgG
- Top Product
- Discover our top product DNM1 Anticorps primaire
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- Indications d'application
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Antigène
- Dynamin 1 (DNM1)
- Autre désignation
- Dynamin-1 (DNM1 Produits)
- Synonymes
- anticorps DNM, anticorps Dnm, anticorps AI838169, anticorps Ftfl, anticorps mKIAA4093, anticorps dnm, anticorps DNM1, anticorps Dnm1, anticorps dnm1, anticorps si:dkey-246l19.2, anticorps dynamin 1, anticorps dynamin-1, anticorps dynamin 1a, anticorps DNM1, anticorps Dnm1, anticorps BACOIKO008_37, anticorps PTRG_07818, anticorps PTRG_08097, anticorps dnm1, anticorps LOC100168088, anticorps LOC100199205, anticorps dnm1a
- Sujet
- Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001, Graham et al., 2002, Tsuboi et al., 2002). Cyclin dependent protein kinase 5 phosphorylates Dynamin at Ser774 and Ser778 that are the phosphorylation sites on Dynamin phosphorylated in vivo (Tan et al., 2003). Phosphorylation of these sites on Dynamin is thought to play a key role in synaptic vesicle trafficking.Synonyms: DNM, DNM1
- ID gène
- 140694
- NCBI Accession
- NP_542420
- UniProt
- P21575
- Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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