GRIA2 anticorps (C-Term)

N° du produit ABIN372655

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIA2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Poisson zèbre (Danio rerio) et Poulet.

Aperçu rapide pour GRIA2 anticorps (C-Term) (ABIN372655)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIA2 anticorps

Épitope: C-Term

Specificité: This antibody is specific for the ~100k GluR2/3 protein.

Réactivité croisée (Details): Species reactivity (expected):Chicken, Human, Mouse and Zebrafish.
Species reactivity (tested):Rat.
Also reacts to: GLUR3

Purification: Affinity Chromatography.

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of rat GluR2/3.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: Glutamate Receptor 2 / GLUR2

Sujet: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

ID gène: 2891

NCBI Accession: NP_000817

UniProt: P42262

Pathways: Signalisation PI3K-Akt