MARCKS anticorps (pSer152, pSer156)
Aperçu rapide pour MARCKS anticorps (pSer152, pSer156) (ABIN372663)
Antigène
Voir toutes MARCKS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer152, pSer156
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Réactivité croisée (Details)
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Species reactivity (expected):Bovine, Chicken, Human, Mouse, Xenopus and Zebrafish.
Species reactivity (tested):Rat. -
Purification
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
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Immunogène
- Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser152,156 of MARCKS.
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Isotype
- IgG
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Indications d'application
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Autre désignation
- MARCKS
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Sujet
- Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) is a major substrate for phosphorylation by protein kinase C (PKC) (Ouimet et al., 1990). The phosphorylation of Ser152/156 can be used as a measure of PKC activation although these sites are also phosphorylated by PRK1 (Palmer et al., 1996) MARCKS is a member of a family of calmodulin binding proteins and phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin (Verghese et al., 1994).Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL
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ID gène
- 10116
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UniProt
- P30009
Antigène
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