OLIG2 anticorps

N° du produit ABIN372693

Cité dans 4 publications. Cet anticorps anti-OLIG2 Polyclonal Lapin (ABIN372693) détecte spécifiquement OLIG2 dans WB, IP, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour OLIG2 anticorps (ABIN372693)

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OLIG2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-OLIG2 anticorps

Specificité: This antibody recognizes the ~32 kDa Olig2 protein in Western blots.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat.

Purification: Protein A Chromatography.

Immunogène: Recombinant Mouse Olig2.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/3000. Immunohistochemistry: 1/1000. Immunocytochemistry: 1/1000. Immunoprecipitation: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 mM Glycine, 200 mM Tris, pH 8.0 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Références pour anticorps anti-OLIG2 (ABIN372693)

Norwood, Franklin, Sharma, DMello: "Histone deacetylase 3 is necessary for proper brain development." dans: The Journal of biological chemistry, Vol. 289, Issue 50, pp. 34569-82, (2014) (PubMed).

Bains, Tourkina, Atkinson, Joseph, Tholanikunnel, Chu, Riemer, Martin, Hoffman: "Loss of caveolin-1 from bronchial epithelial cells and monocytes in human subjects with asthma." dans: Allergy, Vol. 67, Issue 12, pp. 1601-4, (2012) (PubMed).

Davies, Goebel-Goody, Coultrap, Browning: "Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization." dans: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33138-46, (2008) (PubMed).

Guan, Tkatch, Surmeier, Armstrong, Foehring: "Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons." dans: The Journal of physiology, Vol. 581, Issue Pt 3, pp. 941-60, (2007) (PubMed).

Détails sur OLIG2

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Autre désignation: OLIG2

Sujet: Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).Synonyms: BHLHB1, Class B basic helix-loop-helix protein 1, OLIG2, Oligo2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17, bHLHB1

ID gène: 10215

NCBI Accession: NP_005797

UniProt: Q13516