DLG4 anticorps (N-Term)
Aperçu rapide pour DLG4 anticorps (N-Term) (ABIN372707)
Antigène
Voir toutes DLG4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody recognizes the ~95k PSD95 protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Human, Bovine, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat and Mouse. -
Purification
- Affinity Chromatography.
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Immunogène
- Peptide corresponding to amino acid residues from the N-terminal region of Rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).
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Isotype
- IgG
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Indications d'application
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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Autre désignation
- DLG4 / PSD95
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Sujet
- PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).Synonyms: DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
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ID gène
- 29495
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NCBI Accession
- NP_062567
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UniProt
- P31016
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Pathways
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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