Tyrosine Hydroxylase anticorps

N° du produit ABIN372735

Cet anticorps anti-Tyrosine Hydroxylase est un anticorps Mouton Polyclonal détectant Tyrosine Hydroxylase dans WB, IF et IHC (fro). Adapté pour Mammifères.

Aperçu rapide pour Tyrosine Hydroxylase anticorps (ABIN372735)

Antigène: Tyrosine Hydroxylase (TH)

Reactivité: Mammifères

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Tyrosine Hydroxylase anticorps

Specificité: Specific for the ~60k Tyrosine Hydroxylase protein in Western Blots of Rat brain lysates and PC-12 cells stimulated by Okadaic Acid. The antibody cross reacts with all mammalian and at least some non-mammalian forms of the enzyme in Western blots and in IHC/IF.

Réactivité croisée (Details): Species reactivity (tested):Mammalia.

Purification: Affinity Chromatography.

Immunogène: Native rat tyrosine hydroxylase, purified from pheochromocytoma.

Isotype: IgG

Information d'application

Indications d'application: Western Blot/Dot Blot: 1/1,000. Immunofluorescence 1/1000 (Frozen Sections). Immunohistochemistry on Frozen Sections: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur Tyrosine Hydroxylase

Antigène: Tyrosine Hydroxylase (TH)

Autre désignation: Tyrosine 3-Monooxygenase (TH)

Sujet: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000, Salvatore et al., 2001).Synonyms: TYH, Tyrosine 3-hydroxylase

ID gène: 25085

NCBI Accession: NP_036872

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour