BIRC7 anticorps (C-Term)

N° du produit ABIN374091

Détail du produit anti-BIRC7 anticorps

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-RAPVRSRVRT

Specificité: This antibody is expected to recognise both reported isoforms of BIRC7 (as represented by NP_647478.1 and NP_071444.1)

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_647478.1, NP_071444.1. Genename: BIRC7

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 4000. Western blot: 0.1 - 1.0 μg/mL. Experiments gave bands at approx 30 kDa and 30 kDa inhuman acute lymphoblastic leukaemia MOLT4 lysate after 0.3 μg/mL antibody staining. These bands correspond to the reported isoforms with calculated MW of 32.0 kDaaccording to NP_647478.1 and 30.0 kDa according to NP_071444.1.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: BIRC7 / LIVIN (BIRC7 Produits)

Synonymes: anticorps KIAP, anticorps LIVIN, anticorps ML-IAP, anticorps MLIAP, anticorps RNF50, anticorps EIAP/XLX, anticorps XLX, anticorps kiap, anticorps livin, anticorps ml-iap, anticorps mliap, anticorps rnf50, anticorps xEIAP, anticorps RGD1562883, anticorps zgc:165605, anticorps E130019N06, anticorps Livin, anticorps birc7, anticorps bird7a, anticorps xEIAP/XLX, anticorps xlx, anticorps EIAP/XLX-B, anticorps birc7b, anticorps baculoviral IAP repeat containing 7, anticorps baculoviral IAP repeat-containing 7, anticorps baculoviral IAP repeat-containing 7 (livin), anticorps baculoviral IAP repeat containing 7 S homeolog, anticorps baculoviral IAP repeat containing 7 L homeolog, anticorps BIRC7, anticorps birc7, anticorps Birc7, anticorps birc7.S, anticorps birc7.L

Sujet: Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

ID gène: 79444

NCBI Accession: NP_647478

UniProt: Q96CA5