BAG2 anticorps (C-Term)

N° du produit ABIN374110

Cet anticorps Chèvre Polyclonal détecte spécifiquement BAG2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour BAG2 anticorps (C-Term) (ABIN374110)

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAG2 anticorps

Épitope: C-Term

Séquence: CSKTLQQNAE SRFN

Specificité: This antibody detects BAG2 at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_004273.1. Genename: BAG2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 8000. Western blot: 0.1-0.3 μg/mL. Approx 25 kDa band observed in Human HeLa lysates(calculated MW of 23.5 kDa according to NP_004273.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur BAG2

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Autre désignation: BAG2

Sujet: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.Synonyms: BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2

ID gène: 9532

NCBI Accession: NP_004273

UniProt: O95816