Annexin A2 anticorps (N-Term)

N° du produit ABIN374164

Cet anticorps Chèvre Polyclonal détecte spécifiquement Annexin A2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Porc.

Aperçu rapide pour Annexin A2 anticorps (N-Term) (ABIN374164)

Antigène: Annexin A2 (ANXA2)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin A2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Annexin A2 anticorps

Épitope: N-Term

Séquence: STVHEILCKL SLEGD

Specificité: This antibody is expected to recognize both reported isoforms.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Cow, and Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from N Terminus of the protein sequence according to NP_001002858.1, NP_004030.1, NP_001002857.1, NP_001129487.1. Genename: ANXA2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 35 kDa band observed in lysates of cell lines A431 andA549 (calculated MW of 38.6 kDa according to NP_004030.1 and NP_001002857.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Détails sur Annexin A2

Antigène: Annexin A2 (ANXA2)

Autre désignation: Annexin A2 / ANXA2

Sujet: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ANX2, ANX2L4, Annexin II, Annexin-2, CAL1H, Calpactin I heavy chain, Chromobindin-8, LPC2D, Lipocortin II, Placental anticoagulant protein IV, Protein I, p36

ID gène: 302

NCBI Accession: NP_001002858

UniProt: P07355

Pathways: S100 Proteins