Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Séquence
C-KRKRETDDEG EDD
Specificité
This antibody does NOT recognize the TNF family member also known as APRIL - Gene ID number 8741. However this antibody may cross-react with ANP32A (GeneID 8125).
Réactivité croisée (Details)
Species reactivity (expected):Mouse, Rat, Canine (Dog), Pig, Cow. Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogène
Peptide from C Terminus of the protein sequence according to NP_006392.1 Genename: ANP32B
Peptide ELISA: Limit dilution: 1/1000. Western blot: 0.3-1 μg/mL. Approx 26 kDa band observed in Human lymph node lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps APRIL, anticorps PHAPI2, anticorps SSP29, anticorps 2410015B15Rik, anticorps PAL31, anticorps PHAPI2a, anticorps Ssp29, anticorps cb908, anticorps fa99a11, anticorps wu:fa28c10, anticorps wu:fa99a11, anticorps wu:fb40e12, anticorps zgc:77745, anticorps hLAMP-1, anticorps MGC80871, anticorps ANP32B, anticorps MGC69373, anticorps SLAN, anticorps acidic nuclear phosphoprotein 32 family member B, anticorps acidic (leucine-rich) nuclear phosphoprotein 32 family, member B, anticorps acidic nuclear phosphoprotein 32 family member B L homeolog, anticorps acidic leucine-rich nuclear phosphoprotein 32 family member B, anticorps ANP32B, anticorps Anp32b, anticorps anp32b, anticorps anp32b.L, anticorps LOC494442
Sujet
PHAPI2 / APRIL is a multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. It is required for the progression from the G1 to the S phase. It is an anti-apoptotic protein which functions as a caspase-3 inhibitor. It has no phosphatase 2A (PP2A) inhibitor activity.Synonyms: APRIL, Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, PHAPI2, SSP29, Silver-stainable protein SSP29