GSTM1 anticorps (C-Term)

N° du produit ABIN374509

Cet anticorps Chèvre Polyclonal détecte spécifiquement GSTM1 dans WB. Il présente une réactivité envers Humain et Singe.

Aperçu rapide pour GSTM1 anticorps (C-Term) (ABIN374509)

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reactivité: Humain, Singe

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GSTM1 anticorps

Épitope: C-Term

Specificité: This antibody reacts to GSTM1 and will also recognise GSTM2 protein.

Purification: Affinity chromatography

Immunogène: Peptide with sequence CVFSKMAVWGNK, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GSTM1

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Autre désignation: GSTM1

Sujet: Glutathione S transferases are encoded by two distinct supergene families and a total of eight distinct classes of the soluble cytoplasmic mammalian glutathione S transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of these enzymes, to which GSTM1 and 2 belong, functions in the detoxification of electrophilic compounds by conjugation with glutathione. The genes encoding the mu class of enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs and null mutations of this gene have been linked with an increase in a number of cancers.Synonyms: GST class-mu 1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, Glutathione S-transferase Mu 1

ID gène: 2944, 9606

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity