LIM Domain Binding 3 Protein anticorps (Internal Region)

N° du produit ABIN374603

Détail du produit anti-LIM Domain Binding 3 Protein anticorps

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Binding 3 Protein est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to LDB3.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-KSQNKPEDEADE, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/2000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LIM Domain Binding 3 Protein

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Autre désignation: LDB3 (LDB3 Produits)

Synonymes: anticorps CMD1C, anticorps CYPHER, anticorps LDB3Z1, anticorps LDB3Z4, anticorps LVNC3, anticorps MFM4, anticorps ORACLE, anticorps PDLIM6, anticorps ZASP, anticorps AW742271, anticorps ldb3l, anticorps zgc:55814, anticorps wu:fi31d08, anticorps ldb3, anticorps MGC52706, anticorps MGC75668, anticorps RGD1564875, anticorps LDB3, anticorps cypher, anticorps hm:zehn1639, anticorps zehn1639, anticorps LIM domain binding 3, anticorps LIM domain binding 3b, anticorps LIM domain binding 3 S homeolog, anticorps LIM domain binding 3a, anticorps LDB3, anticorps Ldb3, anticorps ldb3b, anticorps ldb3.S, anticorps ldb3, anticorps ldb3a

Sujet: LDB3 (LIM domain-binding protein 3) may function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. It interactes with various PKC isoforms and with the C-terminal region of ACTN2 via its LIM and PDZ domains respectively. It also interacts with MYOZ1, MYOZ2 and MYOZ3. 6 isoforms are produced by alternative splicing. Defects in LDB3 are a cause of dilated cardiomyopathy 1A, a disorder characterized by cardiac dilation and reduced systolic function, as well as ZASP-related myofibrillar myopathy, an autosomal dominant myopathy that is characterized by distal muscle weakness with signs of cardiomyopathy and neuropathy.Synonyms: KIAA0613, LIM domain-binding protein 3, ZASP

ID gène: 11155, 9606

UniProt: O75112