Stathmin 1 anticorps (C-Term)

N° du produit ABIN374648

Il existe 2+ publications pour ce produit. L’anticorps anti-Stathmin 1 Polyclonal Chèvre est utilisé pour la détection de Stathmin 1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour Stathmin 1 anticorps (C-Term) (ABIN374648)

Antigène: Stathmin 1 (STMN1)

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Stathmin 1 anticorps

Épitope: C-Term

Specificité: This antibody is expected to cross-react with isoform 1a (NP_005554.1, NP_981944.1, NP_981946.1) only. The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide (C-KNKESKDPADETEAD) from C-terminus of Human STMN1 (NP_005554.1, NP_981944.1, NP_981946.1)

Information d'application

Indications d'application: ELISA: 1/1000. Western Blot: 1-3 μg/mL. Immunohistochemistry on Paraffin Sections: 3.75 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Stathmin 1 (ABIN374648)

Watabe-Rudolph, Song, Lausser, Schnack, Begus-Nahrmann, Scheithauer, Rettinger, Otto, Tumani, Thal, Attems, Jellinger, Kestler, von Arnim, Rudolph: "Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease." dans: Neurology, Vol. 78, Issue 8, pp. 569-77, (2012) (PubMed).

Wallukat, Muñoz Saravia, Haberland, Bartel, Araujo, Valda, Duchen, Diaz Ramirez, Borges, Schimke: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." dans: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Stathmin / STMN1

Sujet: STMN1 is a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

Poids moléculaire: 17.3kDa (NP_005554.1, NP_981944.1 and NP_981946.1).

ID gène: 3925, 9606

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules