Serotonin Receptor 3A anticorps (Internal Region)

N° du produit ABIN374713

Cet anticorps Chèvre Polyclonal détecte spécifiquement Serotonin Receptor 3A dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain et Rat. Il a été cité dans 2+ publications.

Aperçu rapide pour Serotonin Receptor 3A anticorps (Internal Region) (ABIN374713)

Antigène: Serotonin Receptor 3A (HTR3A)

Reactivité: Humain, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 3A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-Serotonin Receptor 3A anticorps

Épitope: Internal Region

Séquence: C-GPQDFEKSPR DR

Specificité: This antibody is expected to recognize all three reported isoforms (NP_998786.2, NP_000860.2, NP_001155244.1).

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence Genename: HTR3A

Information d'application

Indications d'application: ELISA: 1/128000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Serotonin Receptor 3A (ABIN374713)

do Amaral, Ueno, Oliveira, Borsonello, Vanzela, Ribeiro, Alves, Barbosa, Carneiro, Boschero: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." dans: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).

Lu, Hsieh, Dun, Oprea, Wang, Luo, Lin, Chang, Lee: "Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats." dans: Gastroenterology, Vol. 137, Issue 3, pp. 1040-50, (2009) (PubMed).

Détails sur Serotonin Receptor 3A

Antigène: Serotonin Receptor 3A (HTR3A)

Sujet: 5-hydroxytryptamine (serotonin) receptors is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The 5HT3A receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

ID gène: 3359

NCBI Accession: NP_000860

UniProt: P46098

Pathways: Synaptic Membrane