COMT anticorps (Internal Region)

N° du produit ABIN374718

Cet anticorps anti-COMT Polyclonal Chèvre (ABIN374718) détecte spécifiquement COMT dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour COMT anticorps (Internal Region) (ABIN374718)

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp COMT est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-COMT anticorps

Épitope: Internal Region

Specificité: This antibody is expected to recognizes both reported isoforms of COMT (NP_000745.1 and NP_009294.1).

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-QDIIPQLKKKYDVD, from the internal region of the protein sequence (NP_000745.1 and NP_009294.1). Genename: COMT

Information d'application

Indications d'application: Peptide ELISA: Detection Limit Dilution: 1/64000. Western Blot: 0.03-0.1 μg/mL. Approx 28 kDa band and faint 28 kDa band observed inhuman testis lysates (calculated MW of 30.8 kDa according to NP_000745.1 and 24.8 kDaaccording to NP_009294.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur COMT

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Autre désignation: COMT

Sujet: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase

ID gène: 1312, 9606

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome