Fibulin 5 anticorps (C-Term, Internal Region)

N° du produit ABIN374733

Cet anticorps anti-Fibulin 5 Polyclonal Chèvre (ABIN374733) détecte spécifiquement Fibulin 5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour Fibulin 5 anticorps (C-Term, Internal Region) (ABIN374733)

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Fibulin 5 anticorps

Épitope: C-Term, Internal Region

Specificité: This antibody reacts to FBLN5.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-RPIKGPREIQLDLE, from the internal region (near the C Terminus) of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: Fibulin-5

Sujet: Fibulin 5(FBLN5), the active form of which is about 66 kDa (unprocessed precursor 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin 5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin 5 is also a good marker of skin ageing and that the earlier loss of fibulin 5 may involve age-dependent changes in other elastic fibre components.Synonyms: DANCE, Developmental arteries and neural crest EGF-like protein, FBLN5, FIBL-5, UP50, Urine p50 protein

ID gène: 10516

NCBI Accession: NP_006320

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome