Gelsolin anticorps (Internal Region)
Aperçu rapide pour Gelsolin anticorps (Internal Region) (ABIN374752)
Antigène
Voir toutes Gelsolin (GSN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This antibody reacts to Gelsolin.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence C-PRLKDKKMDAHP, from the internal region of the protein sequence
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Indications d'application
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Gelsolin (GSN)
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Autre désignation
- Gelsolin
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Sujet
- Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.Synonyms: AGEL, Actin-depolymerizing factor, Brevin, GSN
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ID gène
- 2934
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NCBI Accession
- NP_000168
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UniProt
- P06396
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
Antigène
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