MANF anticorps (Internal Region)

N° du produit ABIN374894

L’anticorps anti-MANF Polyclonal Chèvre est utilisé pour la détection de MANF dans des échantillons de Humain, Souris, Rat et Chien. Il a été validé pour WB.

Aperçu rapide pour MANF anticorps (Internal Region) (ABIN374894)

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MANF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MANF anticorps

Épitope: Internal Region

Specificité: This antibody reacts to ARMET.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence KFCREARGKENR, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MANF

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Autre désignation: ARMET / ARP

Sujet: ARMET, also known as MANF, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, ARMET enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, ARMET has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of ARMET has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.Synonyms: Arginine-rich protein, MANF, Mesencephalic astrocyte-derived neurotrophic factor

ID gène: 7873, 9606

UniProt: P55145