KPNA6 anticorps (Internal Region)

N° du produit ABIN374979

Cet anticorps anti-KPNA6 Polyclonal Chèvre (ABIN374979) détecte spécifiquement KPNA6 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour KPNA6 anticorps (Internal Region) (ABIN374979)

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-KPNA6 anticorps

Épitope: Internal Region

Specificité: This antibody detects KPNA6.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, Bovine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography.

Immunogène: Peptide with sequence C-STTGESVITREMVE, from the internal of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KPNA6

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Autre désignation: KPNA6 / Importin alpha-7

Sujet: Nucleocytoplasmic transport, a signal and energy dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.Synonyms: IPOA7, KPNA6, Karyopherin subunit alpha-6

ID gène: 23633

NCBI Accession: NP_036448

UniProt: O60684

Pathways: Protein targeting to Nucleus