KPNA6 anticorps (N-Term)
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- Antigène Voir toutes KPNA6 Anticorps
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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Épitope
- AA 70-120, N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KPNA6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purification
- KPNA6 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- KPNA6 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA6. The immunogen is located within amino acids 70 - 120 of KPNA6.
- Isotype
- IgG
- Top Product
- Discover our top product KPNA6 Anticorps primaire
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- Indications d'application
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KPNA6 antibody can be used for detection of KPNA6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- KPNA6 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- KPNA6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
- Autre désignation
- KPNA6 (KPNA6 Produits)
- Synonymes
- anticorps IPOA7, anticorps Kpna5, anticorps NPI-2, anticorps KPNA7, anticorps karyopherin subunit alpha 6, anticorps karyopherin (importin) alpha 6, anticorps karyopherin alpha 6 (importin alpha 7), anticorps karyopherin alpha 6 (importin alpha 7) S homeolog, anticorps KPNA6, anticorps Kpna6, anticorps kpna6.S
- Sujet
- KPNA6 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6. Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation, possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation. KPNA6 also interacts with the Rev protein of HIV-1 and promote its nuclear import.
- ID gène
- 23633
- UniProt
- O60684
- Pathways
- Protein targeting to Nucleus
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